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Environmental Research 117

Overview of articles on POPs in a new issue of the Environmental Research journal.

Upstream adverse effects in risk assessment: A model of polychlorinated biphenyls, thyroid hormone disruption and neurological outcomes in humans

Pages 90-99
Amber Wise, Fred Parham, Daniel A. Axelrad, Kathryn Z. Guyton, Christopher Portier, Lauren Zeise, R. Thomas Zoeller, Tracey J. Woodruff

  • We model in humans: prenatal PCB exposures and thyroid hormones (TH) and prenatal TH and childhood IQ.
  • We compare the combination of the two relationships with models of prenatal PCB exposures and childhood IQ.
  • PCBs are associated with decreasing TH and decreasing IQ, some confidence intervals include 0.
  • PCBs and thyroid hormones plus thyroid hormones and IQ estimate PCBs and IQ.

Exposure to polycyclic aromatic hydrocarbons and serum inflammatory markers of cardiovascular disease

Pages 132-137
John D. Clark III, Berrin Serdar, David J. Lee, Kristopher Arheart, James D. Wilkinson, Lora E. Fleming

  • Polycyclic aromatic hydrocarbon metabolites are not associated with cardiovascular biomarkers.
  • No consistent relationships between exposure and outcome were found independent of tobacco use.
  • Polycyclic aromatic hydrocarbon exposure is not a major contributor to cardiovascular disease.

13.8.2012


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